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Lost count how many blue drain plugs on the 4.5 250 Bravo 3 i found 3 seems there is 4 just cant remember.

One at the thermostat is usually the vent, suggest you may want to check the owners manual, not sure what point drain system you have, but also suggest you replace the plugs every few years and grease the threads. The blue plastic degrades with the heat. Also if your winterizing suggest you also remove a lower hose connection because the blue plug can clog. if you never removed the plugs before, get comfortable before you unscrew, no angles. Good luck

Thanks SAB220